I can only really answer this with a circular argument: if by "first request" you mean "first request of something that's in the swap file", then yes, a page fault will be generated. If it requests something that isn't in the swap file then you won't get a page fault.
A page fault occurs when a page the OS wants to load has been moved out to swap, and this is not dependent on memory contents. RAM can be full, empty or anywhere in between; if the data wanted is in swap, then you will get a page fault.
Emptying RAM won't necessarily move stuff from the swap file back into RAM; it will normally be left there until it's needed.