If you are using VB.NET then
Public Class Form1
Dim da As OleDbDataAdapter
Dim ds As New DataSet
Dim con As New OleDb.OleDbConnection("Provider=Microsoft.Jet.OLEDB.4.0;Data Source =C:\db1.mdb;") 'you can edit the source as you like....
Private Sub Form1_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load
da = New OleDbDataAdapter("Select * from student", con) 'student is table's name
'This is basic, i would advise you to read books for more or Google it.
If you are using VB6 then it different method for this. You will need to add Reference manually to the Project and it's called ADODB
Public con As New ADODB.Connection 'Database connection string
Public rsMain As New ADODB.Recordset 'Database record set
Private Sub ConnectToDB
con.Open ("Provider=Microsoft.Jet.OLEDB.4.0;Data Source="C:\db1.mdb")
rsMain.Open "Select * from Table1", con, OpenDynamic, LockOptimistic
'Now you can use rsMain to retrieve and add data to your database
It seems like you have never done this before so I would advice you to read books and gain knowledge on how Databases work, as it'll be very helpful in future. And don't forget GOOGLE.